I actually quite like the layout - has got great potential!
Unless you want major changes, i'd suggest the following.
As losercore mentioned - right column is a bit too far out - try containing it a bit more.
My biggest gripe with it, is the overall color theme and fonts used. I prefer a basic layout, but the colors just seem a bit "too basic". Have a look at your favorite sites and take note of the themes they use. With the fonts - keep it consistent. It gives a much more comfortable feel.
And most importantly - keep a consistent feel throughout the whole site (try tying the theme of the blog with the rest of the site). My "experience" changed when i moved from the blog to the main site, and back.
Looking forward to how it'll turn out!